BDBM802072 US20260108613, Compound A17::methyl (S)-3-((2S,4R)-1-((S)- 5-acetyl-3,8,8-trimethyl- 4,5,6,7,8,9-hexahydro-[1,2,3] triazolo[1,5-a][1,4]diazocine- 9-carbonyl)-4-hydroxypyrrol- idine-2-carboxamido)-3-(4-(4- methylthiazol-5-yl)phenyl)- propanoate

SMILES COC(=O)C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@H]1n2nnc(C)c2CN(C(C)=O)CCC1(C)C)c1ccc(-c2scnc2C)cc1

InChI Key InChIKey=JUEUGGAPUURSLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802072   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 802072BDBM802072(methyl (S)-3-((2S,4R)-1-((S)- 5-acetyl-3,8,8-trime...)
Affinity DataIC50: 107nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent