BDBM802073 US20260108613, Compound A20::ethyl (R)-7-((2S,4R)-4- hydroxy-2-(((S)-1-(4-(4-meth- ylthiazol-5-yl)phenyl)ethyl)- carbamoyl)pyrrolidine-1- carbonyl)-6,6-dimethyl- 4,5,6,7-tetrahydrobenzo[d] isoxazole-3-carboxylate

SMILES CCOC(=O)c1noc2c1CCC(C)(C)[C@H]2C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](C)c1ccc(-c2scnc2C)cc1

InChI Key InChIKey=YEDFHAIEFUOJLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802073   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 802073BDBM802073(ethyl (R)-7-((2S,4R)-4- hydroxy-2-(((S)-1-(4-(4-me...)
Affinity DataIC50: 71.5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent