BDBM802074 (2S,4R)-1-((S)-3-(3-(2-chloro- 3-hydroxyphenyl)propyl)-7,7- dimethyl-7,8-dihydro-4H,6H- [1,2,3]triazolo[5,1-c][1,4] oxazepine-8-carbonyl)-4- hydroxy-N-((S)-1-(4-(4-meth- ylthiazol-5-yl)phenyl)ethyl)- pyrrolidine-2-carboxamide::US20260108613, Compound A21

SMILES Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H]2n3nnc(CCCc4cccc(O)c4Cl)c3COCC2(C)C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802074   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 802074BDBM802074((2S,4R)-1-((S)-3-(3-(2-chloro- 3-hydroxyphenyl)pro...)
Affinity DataIC50: 2.84nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent