BDBM802084 (1R,2S,5S)-N-(4-(cyclopropylamino)-3,4- dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2- yl)-3-((E)-3-(2,4-difluorophenyl)acryloyl)- 6,6-dimethyl-3-azabicyclo[3.1.0]hexane- 2-carboxamide::US20260109672, Example 7

SMILES CC1(C)[C@@H]2[C@@H](C(=O)NC(C[C@@H]3CCNC3=O)C(=O)C(=O)NC3CC3)N(C(=O)/C=C/c3ccc(F)cc3F)C[C@@H]21

InChI Key InChIKey=ZJCCPGWCTQEREP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802084   

TargetReplicase polyprotein 1a(2019-nCoV)
Nxera Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 802084BDBM802084((1R,2S,5S)-N-(4-(cyclopropylamino)-3,4- dioxo-1-((...)
Affinity DataKi:  63.1nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent