BDBM802127 US20260109684, RAGE 406R

SMILES N#Cc1ccc2c(CN3CCOCC3)cc(-c3ccc([C@H]4CCC(=O)N4)cc3)nc2c1

InChI Key InChIKey=MUVCLMZDXXUHRB-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802127   

TargetAdvanced glycosylation end product-specific receptor(Human)
New York University

US Patent
LigandChemical structure of BindingDB Monomer ID 802127BDBM802127(US20260109684, RAGE 406R)
Affinity DataKd:  0.600nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent