BDBM802297 N-hydroxy-4-(2-(2-oxo-1-oxa- 3,8-diazaspiro[4.5]decan-8- yl)pyrimidin-4-yl)benzamide::US20260109690, Compound I-26

SMILES O=C1NCC2(CCN(c3nccc(-c4ccc(C(=O)NO)cc4)n3)CC2)O1

InChI Key InChIKey=SDEMOAVUDTWFRK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802297   

TargetHistone deacetylase 6(Human)
Baerenkraft Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802297BDBM802297(N-hydroxy-4-(2-(2-oxo-1-oxa- 3,8-diazaspiro[4.5]de...)
Affinity DataIC50: 1.00E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent