BDBM802313 (S)-6-(4''-amino-4''H,6''H-spiro [piperidine-4,5''-pyrrolo[1,2- b]pyrazol]-1-yl)-3-(2,3- dichlorophenyl)-2,5- dimethylpyrimidin-4(3H)-one::US20260109699, Example 3

SMILES Cc1c(N2CCC3(CC2)Cn2nccc2[C@H]3N)nc(C)n(-c2cccc(Cl)c2Cl)c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802313   

LigandChemical structure of BindingDB Monomer ID 802313BDBM802313((S)-6-(4'-amino-4'H,6'H-spiro [piperidine-4,5'-pyr...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent