BDBM802380 (S)-1-(6-(2,3-difluorophenyl) pyrido[2,3-b]pyrazin-2-yl)- 4'H,6'H-spiro[piperidine-4,5'- pyrrolo[1,2-b]pyrazol]-4'- amine::US20260109699, Example 8

SMILES N[C@@H]1c2ccnn2CC12CCN(c1cnc3nc(-c4cccc(F)c4F)ccc3n1)CC2

InChI Key InChIKey=XPPPSXXPFMJAIF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802380   

LigandChemical structure of BindingDB Monomer ID 802380BDBM802380((S)-1-(6-(2,3-difluorophenyl) pyrido[2,3-b]pyrazin...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent