BDBM802456 (S)-1-(3-(2-chloro-3-fluorophenyl) imidazo[1,5-a]pyrazin-8- yl)-4'H,6'H-spiro[piperidine-4,5'- pyrrolo[1,2-b]pyrazol]-4'- amine::US20260109699, Example 14

SMILES N[C@@H]1c2ccnn2CC12CCN(c1nccn3c(-c4cccc(F)c4Cl)ncc13)CC2

InChI Key InChIKey=SPAWFHSNIPTTNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802456   

LigandChemical structure of BindingDB Monomer ID 802456BDBM802456((S)-1-(3-(2-chloro-3-fluorophenyl) imidazo[1,5-a]p...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent