BDBM802500 (S)-1-(5-((2,3-dichlorophenyl)thio)- 3-methylpyrazin-2-yl)- 4'H,6'H-spiro[piperidine-4,5'- pyrrolo[1,2-b]pyrazol]-4'- amine::US20260109699, Example 17

SMILES Cc1nc(Sc2cccc(Cl)c2Cl)cnc1N1CCC2(CC1)Cn1nccc1[C@H]2N

InChI Key InChIKey=GLDQDTRBVQKQIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802500   

LigandChemical structure of BindingDB Monomer ID 802500BDBM802500((S)-1-(5-((2,3-dichlorophenyl)thio)- 3-methylpyraz...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent