BDBM802616 (S)-1-(5-((2-fluoro-4-methoxyphenyl) thio)pyrazin-2-yl)- 4''H,6''H-spiro[piperidine-4,5''- pyrrolo[1,2-b]pyrazol]-4''- amine::US20260109699, Example 64

SMILES COc1ccc(Sc2cnc(N3CCC4(CC3)Cn3nccc3[C@H]4N)cn2)c(F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802616   

LigandChemical structure of BindingDB Monomer ID 802616BDBM802616((S)-1-(5-((2-fluoro-4-methoxyphenyl) thio)pyrazin-...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand Info
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Date in BDB:
9/3/2026
Entry Details
US Patent