BDBM802619 (S)-1-(5-((8-(trifluoromethyl) quinolin-5-yl)thio)pyrazin-2- yl)-4''H,6''H-spiro[piperidine-4,5''- pyrrolo[1,2-b]pyrazol]-4''- amine::US20260109699, Example 67

SMILES N[C@@H]1c2ccnn2CC12CCN(c1cnc(Sc3ccc(C(F)(F)F)c4ncccc34)cn1)CC2

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802619   

LigandChemical structure of BindingDB Monomer ID 802619BDBM802619((S)-1-(5-((8-(trifluoromethyl) quinolin-5-yl)thio)...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent