BDBM802629 (S)-1-(5-((2,4,5-trifluorophenyl)thio) pyrazin-2-yl)-4''H,6''H- spiro[piperidine-4,5''-pyrrolo [1,2-b]pyrazol]-4''-amine::US20260109699, Example 77

SMILES N[C@@H]1c2ccnn2CC12CCN(c1cnc(Sc3cc(F)c(F)cc3F)cn1)CC2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802629   

LigandChemical structure of BindingDB Monomer ID 802629BDBM802629((S)-1-(5-((2,4,5-trifluorophenyl)thio) pyrazin-2-y...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent