BDBM8035 (2S)-N-[(2S,3S)-4-[(5S)-5-[(4-bromophenyl)methyl]-2,4-dioxoimidazolidin-1-yl]-3-hydroxy-1-phenylbutan-2-yl]-3-methyl-2-(pyridin-2-ylformamido)butanamide::(5S)-5-(p-Bromobenzyl)-1-{(2S,3R)-2-hydroxy-4-phenyl-3-[(picolyl-L-valinyl)amino]butyl}imidazolidine-2,4-dione::hydroxyethylamine-based inhibitor 18

SMILES CC(C)[C@H](NC(=O)c1ccccn1)C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)Cn1c(Cc2ccc(Br)cc2)c(O)[nH]c1=O

InChI Key InChIKey=SOOFIQWYVYSAHB-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8035   

TargetPlasmepsin II(Plasmodium falciparum)
Uppsala University

LigandPNGBDBM8035((5S)-5-(p-Bromobenzyl)-1-{(2S,3R)-2-hydroxy-4-phen...)
Affinity DataKi:  1.90E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetCathepsin D(Human)
Uppsala University

LigandPNGBDBM8035((5S)-5-(p-Bromobenzyl)-1-{(2S,3R)-2-hydroxy-4-phen...)
Affinity DataKi: >2.00E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetCathepsin D(Human)
Uppsala University

LigandPNGBDBM8035((5S)-5-(p-Bromobenzyl)-1-{(2S,3R)-2-hydroxy-4-phen...)
Affinity DataKi: >2.00E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed
TargetPlasmepsin I(malaria parasite P. falciparum)
Uppsala University

LigandPNGBDBM8035((5S)-5-(p-Bromobenzyl)-1-{(2S,3R)-2-hydroxy-4-phen...)
Affinity DataKi: >2.00E+3nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/1/2006
Entry Details Article
PubMed