BDBM803688 2-((6-ethoxy-2-((1r,4r)-4-hydroxycyclohexyl)-2H-indazol-5-yl)carbamoyl)-6-methylpyridine 1-oxide::US12617770, Compound 016

SMILES CCOc1cc2nn([C@H]3CC[C@H](O)CC3)cc2cc1NC(=O)c1cccc(C)[n+]1[O-]

InChI Key InChIKey=JMTDFQOQPQJJCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803688   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Wuhan Createrna Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 803688BDBM803688(2-((6-ethoxy-2-((1r,4r)-4-hydroxycyclohexyl)-2H-in...)
Affinity DataIC50: 8.10nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent