BDBM803702 US20260116889, Example 40

SMILES CN1CCCNc2nc(ncc2Cl)Nc2cc(ccc2OC(F)(F)F)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 803702   

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Whan In Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803702BDBM803702(US20260116889, Example 40)
Affinity DataIC50: 3.81nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2026
Entry Details
US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Whan In Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803702BDBM803702(US20260116889, Example 40)
Affinity DataIC50: 5.47nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/9/2026
Entry Details
US Patent