BDBM803710 2-((2-((1r,4r)-4-(cyanomethyl)-4-hydroxycyclohexyl)-6-methoxy-2H-indazol-5-yl)carbamoyl)-6-cyclopropylpyridine 1-oxide::US12617770, Compound 176

SMILES COc1cc2nn([C@H]3CC[C@@](O)(CC#N)CC3)cc2cc1NC(=O)c1cccc(C2CC2)[n+]1[O-]

InChI Key InChIKey=RSNKELYGRJSYIE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803710   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Wuhan Createrna Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 803710BDBM803710(2-((2-((1r,4r)-4-(cyanomethyl)-4-hydroxycyclohexyl...)
Affinity DataIC50: 4.30nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent