BDBM803717 2-((6-(dimethylamino)-2-((1s,4s)-4-hydroxy-4-methylcyclohexyl)-2H-indazol-5-yl)carbamoyl)-6-methylpyridine 1-oxide::US12617770, Compound 287

SMILES Cc1cccc(C(=O)Nc2cc3cn([C@H]4CC[C@@](C)(O)CC4)nc3cc2N(C)C)[n+]1[O-]

InChI Key InChIKey=NQNYBYYZCRJFSO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803717   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Wuhan Createrna Science and Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 803717BDBM803717(2-((6-(dimethylamino)-2-((1s,4s)-4-hydroxy-4-methy...)
Affinity DataIC50: 13nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/14/2026
Entry Details
US Patent