BDBM805728 2-methyl-N-(1-(1-methyl-6-(2-methylthiazol- 5-yl)-1H-pyrazolo[3,4-b]pyridin-4- yl)cyclopropyl)-5-((1R,5S)-8-methyl-3,8- diazabicyclo[3.2.1]octan-3-yl)benzamide::US20260125399, Compound 2

SMILES Cc1ncc(-c2cc(C3(NC(=O)c4cc(N5CC6CCC(C5)N6C)ccc4C)CC3)c3cnn(C)c3n2)s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805728   

TargetReplicase polyprotein 1a(2019-nCoV)
Rutgers, The State University Of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 805728BDBM805728(2-methyl-N-(1-(1-methyl-6-(2-methylthiazol- 5-yl)-...)
Affinity DataIC50: 8.00E+7nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent