BDBM805755 (R)-5-(2-(dimethylamino)ethoxy)-2-methyl- N-(1-(1-methyl-6-(1-(2,2,2-trifluoroethyl)- 1H-pyrazol-4-yl)-1H-pyrazolo[3,4-b]pyridin- 4-yl)ethyl)benzamide::US20260125399, Compound 29

SMILES Cc1ccc(OCCN(C)C)cc1C(=O)N[C@H](C)c1cc(-c2cnn(CC(F)(F)F)c2)nc2c1cnn2C

InChI Key InChIKey=QWLHZVYFQLHCOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805755   

TargetReplicase polyprotein 1a(2019-nCoV)
Rutgers, The State University Of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 805755BDBM805755((R)-5-(2-(dimethylamino)ethoxy)-2-methyl- N-(1-(1-...)
Affinity DataIC50: 3.70E+8nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent