BDBM805794 N-(1-(6-(1-(2-cyanoethyl)-1H-pyrazol-4-yl)- 1-isopropyl-1H-pyrazolo[3,4-b]pyridin-4- yl)cyclopropyl)-2-methyl-5-((1R,5S)-8- methyl-3,8-diazabicyclo[3.2.1]octan-3- yl)benzamide::US20260125399, Compound 68

SMILES Cc1ccc(N2CC3CCC(C2)N3C)cc1C(=O)NC1(c2cc(-c3cnn(CCC#N)c3)nc3c2cnn3C(C)C)CC1

InChI Key InChIKey=GHIYVKRHEXBYGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805794   

TargetReplicase polyprotein 1a(2019-nCoV)
Rutgers, The State University Of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 805794BDBM805794(N-(1-(6-(1-(2-cyanoethyl)-1H-pyrazol-4-yl)- 1-isop...)
Affinity DataIC50: 1.18E+8nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent