BDBM805797 N-(1-(1-isopropyl-6-(1-methyl-3- (trifluoromethyl)-1H-pyrazol-5-yl)-1H- pyrazolo[3,4-b]pyridin-4-yl)cyclopropyl)-2- methyl-5-((1R,5S)-8-methyl-3,8- diazabicyclo[3.2.1]octan-3-yl)benzamide::US20260125399, Compound 71

SMILES Cc3ccc(N1CC2CCC(C1)N2C)cc3C(=O)NC7(c5cc(c4cc(C(F)(F)F)nn4C)nc6c5cnn6C(C)C)CC7

InChI Key InChIKey=AXKDESCQWJGGGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805797   

TargetReplicase polyprotein 1a(2019-nCoV)
Rutgers, The State University Of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 805797BDBM805797(N-(1-(1-isopropyl-6-(1-methyl-3- (trifluoromethyl)...)
Affinity DataIC50: 1.06E+8nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK3 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent