BDBM805802 N-(1-(1-isopropyl-6-(3-methylisothiazol-5- yl)-1H-pyrazolo[3,4-b]pyridin-4- yl)cyclopropyl)-2-methyl-5-((1R,5S)-8- methyl-3,8-diazabicyclo[3.2.1]octan-3- yl)benzamide::US20260125399, Compound 76

SMILES Cc1cc(-c2cc(C3(NC(=O)c4cc(N5CC6CCC(C5)N6C)ccc4C)CC3)c3cnn(C(C)C)c3n2)sn1

InChI Key InChIKey=XPQBQBFPPFYJGA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805802   

TargetReplicase polyprotein 1a(2019-nCoV)
Rutgers, The State University Of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 805802BDBM805802(N-(1-(1-isopropyl-6-(3-methylisothiazol-5- yl)-1H-...)
Affinity DataIC50: 1.14E+8nMAssay Description:Compounds of Formula I were screened for their ability to inhibit Tyk2 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent