BDBM805803 N-(1-(1-isopropyl-6-(1-methyl-1H-1,2,3- triazol-4-yl)-1H-pyrazolo[3,4-b]pyridin-4- yl)cyclopropyl)-2-methyl-5-((1R,5S)-8- methyl-3,8-diazabicyclo[3.2.1]octan-3- yl)benzamide::US20260125399, Compound 77

SMILES Cc1ccc(N2CC3CCC(C2)N3C)cc1C(=O)NC1(c2cc(-c3cn(C)nn3)nc3c2cnn3C(C)C)CC1

InChI Key InChIKey=KRUWVSPHZGIKJW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 805803   

TargetReplicase polyprotein 1a(2019-nCoV)
Rutgers, The State University Of New Jersey

US Patent
LigandChemical structure of BindingDB Monomer ID 805803BDBM805803(N-(1-(1-isopropyl-6-(1-methyl-1H-1,2,3- triazol-4-...)
Affinity DataIC50: 7.99E+7nMAssay Description:Compounds of Formula I were screened for their ability to inhibit JAK1 using the general enzyme inhibition assay method, in which the assay mixture c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/17/2026
Entry Details
US Patent