BDBM806528 3-fluoro-4-[5-(4-fluorophenyl)-6-isopropyl-1H-pyrazolo[4,3-g]quinolin-7-yl]benzoic acid (157)::US12624028, Compound 157

SMILES CC(C)c4c(c1ccc(C(=O)O)cc1F)nc3cc2[nH]ncc2cc3c4c5ccc(F)cc5

InChI Key InChIKey=PLAOOWXYMNUCPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 806528   

TargetAlpha-1-antitrypsin/Neutrophil elastase(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 806528BDBM806528(3-fluoro-4-[5-(4-fluorophenyl)-6-isopropyl-1H-pyra...)
Affinity DataIC50: 1.16E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2026
Entry Details
US Patent