BDBM806603 (S)-2-((2-((R)-4(difluoromethyl)-2-oxothiazolidin-3-yl)-8-fluoro-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)amino)-3-methoxypropionamide::US12624050, Example 51
SMILES COC[C@H](Nc4ccc3c2nc(N1C(=O)SC[C@H]1C(F)F)cn2CCOc3c4F)C(N)=O
InChI Key InChIKey=FABJMCXELYBSSQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 806603
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Shanghai Hansoh Biomedical Co.
US Patent
Shanghai Hansoh Biomedical Co.
US Patent
Affinity DataIC50: 6.80nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Shanghai Hansoh Biomedical Co.
US Patent
Shanghai Hansoh Biomedical Co.
US Patent
Affinity DataIC50: 348nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Shanghai Hansoh Biomedical Co.
US Patent
Shanghai Hansoh Biomedical Co.
US Patent
Affinity DataIC50: 1.07E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Shanghai Hansoh Biomedical Co.
US Patent
Shanghai Hansoh Biomedical Co.
US Patent
Affinity DataIC50: 1.15E+3nMAssay Description:Biochemical JAK and Off-Target Kinase Assays. A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kin...More data for this Ligand-Target Pair