BDBM80732 MLS001221393::N-(4-hydroxy-1-naphthalenyl)-2-thiophenesulfonamide::N-(4-hydroxy-1-naphthyl)thiophene-2-sulfonamide::N-(4-hydroxynaphthalen-1-yl)thiophene-2-sulfonamide::N-(4-oxidanylnaphthalen-1-yl)thiophene-2-sulfonamide::SMR000612136::Thiophene-2-sulfonic acid (4-hydroxy-naphthalen-1-yl)-amide::cid_697391

SMILES Oc1ccc(NS(=O)(=O)c2cccs2)c2ccccc12

InChI Key InChIKey=PGMYLDPZRWWFCZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 80732   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM80732(N-(4-oxidanylnaphthalen-1-yl)thiophene-2-sulfonami...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human 6x-His tagged wild type BRAF expressed in Sf9 cells by ELISA based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetHexokinase HKDC1 [W721R](Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM80732(N-(4-oxidanylnaphthalen-1-yl)thiophene-2-sulfonami...)
Affinity DataIC50: 9.75E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetHexokinase HKDC1 [W721R](Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM80732(N-(4-oxidanylnaphthalen-1-yl)thiophene-2-sulfonami...)
Affinity DataIC50: 5.53E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2011
Entry Details
PCBioAssay
TargetTyrosyl-DNA phosphodiesterase 2(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM80732(N-(4-oxidanylnaphthalen-1-yl)thiophene-2-sulfonami...)
Affinity DataIC50: 1.28E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay