BDBM807685 3-(5-Hydroxypyrazin-2-yl)-4-oxo-2-((4-(trifluoromethyl)benzyl)thio)-3,4-dihydropyrazolo[5,1-f][1,2,4]triazine-5-carbaldehyde::US20260132136, Example 15

SMILES O=Cc1cnn2nc(SCc3ccc(C(F)(F)F)cc3)n(C3=NCC(O)N=C3)c(=O)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 807685   

TargetNADPH oxidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807685BDBM807685(3-(5-Hydroxypyrazin-2-yl)-4-oxo-2-((4-(trifluorome...)
Affinity DataIC50: 66nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 5(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807685BDBM807685(3-(5-Hydroxypyrazin-2-yl)-4-oxo-2-((4-(trifluorome...)
Affinity DataIC50: 1.70E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 3(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807685BDBM807685(3-(5-Hydroxypyrazin-2-yl)-4-oxo-2-((4-(trifluorome...)
Affinity DataIC50: 1.80E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807685BDBM807685(3-(5-Hydroxypyrazin-2-yl)-4-oxo-2-((4-(trifluorome...)
Affinity DataIC50: 3.80E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetCytochrome b-245 heavy chain(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807685BDBM807685(3-(5-Hydroxypyrazin-2-yl)-4-oxo-2-((4-(trifluorome...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent