BDBM807715 2-((4-Chlorobenzyl)thio)-5-fluoro-3-(5-hydroxypyrazin-2-yl)pyrazolo[5,1-f][1,2,4]triazin-4(3H)-on::US20260132136, Example 45

SMILES O=c1c2c(F)cnn2nc(SCc2ccc(Cl)cc2)n1-c1cnc(O)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 807715   

TargetNADPH oxidase 4(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807715BDBM807715(2-((4-Chlorobenzyl)thio)-5-fluoro-3-(5-hydroxypyra...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 1(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807715BDBM807715(2-((4-Chlorobenzyl)thio)-5-fluoro-3-(5-hydroxypyra...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetCytochrome b-245 heavy chain(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807715BDBM807715(2-((4-Chlorobenzyl)thio)-5-fluoro-3-(5-hydroxypyra...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 3(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807715BDBM807715(2-((4-Chlorobenzyl)thio)-5-fluoro-3-(5-hydroxypyra...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetNADPH oxidase 5(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 807715BDBM807715(2-((4-Chlorobenzyl)thio)-5-fluoro-3-(5-hydroxypyra...)
Affinity DataIC50: 1.00E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent