BDBM807746 US20260132136, Example 76
SMILES O=c1c2c(F)cnn2nc(SCc2c(F)cc(Cl)cc2F)n1-c1cnc(O)cn1
InChI Key InChIKey=IGQDUQANWMBZCX-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 807746
Affinity DataIC50: 31nMAssay Description:NOX4 inhibition is assessed utilizing HEK293 cells stably overexpressing human NOX4 (hNOX4), generating constitutively high levels of hydrogen peroxi...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluation of the NOX4 inhibitors on NOX1 activity is assessed in HEK293 cells stably overexpressing human NOX1 (hNOX1).Cells are cultured in the DME...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluation of the NOX4 inhibitors on NOX2 activity is assessed in human blood-derived granulocytes.Different concentrations of the test compounds (30...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluation of the NOX4 inhibitors on NOX3 activity is assessed in HEK293 cells stably overexpressing human NOX3 (hNOX3).Cells are cultured in the DME...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Evaluation of the NOX4 inhibitors on NOX5 activity is assessed in HEK293 cells stably overexpressing human NOX5 (hNOX5).Cells are cultured in the DME...More data for this Ligand-Target Pair