BDBM808001 5-((1-(4-((3R,4S)-3- Fluoro-4- (methylamino) pyrrolidin-1-yl)-2- methoxyphenyl)-1H- imidazol-4- yl)amino)pyrazine-2- carbonitrile::US20260132140, Example 164

SMILES CN[C@H]1CN(c2ccc(-n3cnc(Nc4cnc(C#N)cn4)c3)c(OC)c2)C[C@H]1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808001   

TargetSerine/threonine-protein kinase Chk1(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 808001BDBM808001(5-((1-(4-((3R,4S)-3- Fluoro-4- (methylamino) pyrro...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
Benevolentai Bio

US Patent
LigandChemical structure of BindingDB Monomer ID 808001BDBM808001(5-((1-(4-((3R,4S)-3- Fluoro-4- (methylamino) pyrro...)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/23/2026
Entry Details
US Patent