BDBM808084 (E)-methyl 2,4-dimethyl-5-(3-(4-(2,4,4-trimethylpentan-2-yl)phenoxy)acrylamido)benzoate::US12630497, Compound 6-7

SMILES COC(=O)c1cc(NC(=O)/C=C/Oc2ccc(C(C)(C)CC(C)(C)C)cc2)c(C)cc1C

InChI Key InChIKey=KDUKDLSCMUODHQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808084   

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University Industry-Academic Cooperation Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 808084BDBM808084((E)-methyl 2,4-dimethyl-5-(3-(4-(2,4,4-trimethylpe...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Dongguk University Industry-Academic Cooperation Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 808084BDBM808084((E)-methyl 2,4-dimethyl-5-(3-(4-(2,4,4-trimethylpe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent