BDBM808095 Methyl 5-(3-(4-(2,4,4-trimethylpentan-2-yl)phenoxy)propanamido)nicotinate::US12630497, Compound 9-8

SMILES COC(=O)c1cncc(NC(=O)CCOc2ccc(C(C)(C)CC(C)(C)C)cc2)c1

InChI Key InChIKey=MGBVHDCYXYECJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808095   

TargetMalate dehydrogenase, cytoplasmic(Human)
Dongguk University Industry-Academic Cooperation Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 808095BDBM808095(Methyl 5-(3-(4-(2,4,4-trimethylpentan-2-yl)phenoxy...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetMalate dehydrogenase, mitochondrial(Human)
Dongguk University Industry-Academic Cooperation Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 808095BDBM808095(Methyl 5-(3-(4-(2,4,4-trimethylpentan-2-yl)phenoxy...)
Affinity DataIC50: 7.50E+3nMAssay Description:Human V1b receptor was transiently expressed in 293FT cells (Invitrogen). The cells were collected and then homogenated in a 15 mmol/L tris-hydrochlo...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent