BDBM808497 US20260137699, Example 625

SMILES Cc1nc(N)cc(-c2nc3c4c(nc(OCC56CCCN5CC(F)C6)nc4c2Cl)N(C(C)c2cccnc2N)CCO3)c1C(F)(F)F

InChI Key InChIKey=XNUGLARAPXNJKT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 808497   

TargetKRas [G12V]/Son of Sevenless Homolog 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 808497BDBM808497(US20260137699, Example 625)
Affinity DataIC50: 0.120nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent

TargetKRas/Son of Sevenless Homolog 1(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 808497BDBM808497(US20260137699, Example 625)
Affinity DataIC50: 1.20nMAssay Description:The binding of compounds to bromodomain BRD4 (44-168), BRD4 (333-460), and BRD4 (1-477 or 44-460) was assessed using a time resolved fluorescent reso...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent