BDBM808523 (R)-4-chloro-2,5-dimethyl-N-(3-(2- methylpyrrolidine-1- carbonyl)phenyl)benzenesulfonamide::US20260138961, Example 10

SMILES Cc1cc(S(=O)(=O)Nc2cccc(C(=O)N3CCC[C@H]3C)c2)c(C)cc1Cl

InChI Key InChIKey=BCUIPHWVKCQTGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808523   

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808523BDBM808523((R)-4-chloro-2,5-dimethyl-N-(3-(2- methylpyrrolidi...)
Affinity DataIC50: 800nMAssay Description:Human POLĪ³ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent