BDBM808526 (R)-4-chloro-N-(3-fluoro-5-(2- methylpyrrolidine-1-carbonyl)phenyl)- 2,5-dimethylbenzenesulfonamide::US20260138961, Example 13

SMILES Cc1cc(S(=O)(=O)Nc2cc(F)cc(C(=O)N3CCC[C@H]3C)c2)c(C)cc1Cl

InChI Key InChIKey=HDGXUORHOQSTQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808526   

TargetDNA polymerase subunit gamma-1(Human)
Pretzel Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 808526BDBM808526((R)-4-chloro-N-(3-fluoro-5-(2- methylpyrrolidine-1...)
Affinity DataIC50: 6.00E+3nMAssay Description:Human POLĪ³ was incubated with a linear, partially double-stranded template containing an 85 base pair double-stranded DNA stretch and a 15 nucleotide...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/30/2026
Entry Details
US Patent