BDBM808566 N-((S)-1-(((S)-4-(benzylamino)-3, 4-dione-1-((S)-2-oxopyrrolidin-3-yl) but-2-yl) amino)-3-(3-fluorophenyl)-1-oxopropan-2-yl)- quinoline-2-carboxamide::US12636275, Compound A305

SMILES O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](Cc1cccc(F)c1)NC(=O)c1ccc2ccccc2n1

InChI Key InChIKey=JGOUSOXXLSNFPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808566   

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808566BDBM808566(N-((S)-1-(((S)-4-(benzylamino)-3, 4-dione-1-((S)-2...)
Affinity DataIC50: 8.50E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent