BDBM808769 (R)-N-(6-(3-(2-ethoxyphenoxy)piperidin-1-yl)pyrazin-2-yl)-4-nitrobenzamide::US12637440, Example 10

SMILES CCOc1ccccc1O[C@@H]1CCCN(c2cncc(NC(=O)c3ccc([N+](=O)[O-])cc3)n2)C1

InChI Key InChIKey=PUUQWYFVDQIGEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808769   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808769BDBM808769((R)-N-(6-(3-(2-ethoxyphenoxy)piperidin-1-yl)pyrazi...)
Affinity DataIC50: 19nMAssay Description:In vitro DGAT2 analysis was perfomed used a Phospholipid Flast Pate (Perkin Elmer) based on the principle of SPA (Scintillation Proximity Assay). Fi...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/12/2021
Entry Details
US Patent