BDBM808874 (R)-3-(4-(2-((2-(3-((3-ethoxypyridin-2-yl)oxy)piperidin-1-yl)pyrimidin-4-yl)amino)-2-oxoethyl)phenyl)-2,2-dimethylpropanoic acid::US12637440, Example 115

SMILES CCOc1cccnc1O[C@@H]1CCCN(c2nccc(NC(=O)Cc3ccc(CC(C)(C)C(=O)O)cc3)n2)C1

InChI Key InChIKey=RMLGXJMVQLGHJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808874   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808874BDBM808874((R)-3-(4-(2-((2-(3-((3-ethoxypyridin-2-yl)oxy)pipe...)
Affinity DataIC50: 140nMAssay Description:In vitro DGAT2 analysis was perfomed used a Phospholipid Flast Pate (Perkin Elmer) based on the principle of SPA (Scintillation Proximity Assay). Fi...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/12/2021
Entry Details
US Patent