BDBM808881 (R)-2-(4-(3-((2-(3-(2-ethoxyphenoxy)piperidin-1-yl)pyrimidin-4-yl)amino)-3-oxopropyl)phenyl)-2-methylpropanoic acid::US12637440, Example 122

SMILES CCOc1ccccc1O[C@@H]1CCCN(c2nccc(NC(=O)CCc3ccc(C(C)(C)C(=O)O)cc3)n2)C1

InChI Key InChIKey=DOTZXRYUJYYLQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 808881   

TargetDiacylglycerol O-acyltransferase 2(Human)
LG Chem

US Patent
LigandChemical structure of BindingDB Monomer ID 808881BDBM808881((R)-2-(4-(3-((2-(3-(2-ethoxyphenoxy)piperidin-1-yl...)
Affinity DataIC50: 60nMAssay Description:In vitro DGAT2 analysis was perfomed used a Phospholipid Flast Pate (Perkin Elmer) based on the principle of SPA (Scintillation Proximity Assay). Fi...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
4/12/2021
Entry Details
US Patent