BDBM809043 3-amino-N-{(3S,4R)-4-[(4-{1-[1-(2-hydroxyethyl)piperidin-4-yl]-3,3-dimethyl-2,3-dihydro-1H-indol-5-yl}phenyl)methoxy]oxolan-3-yl}-6-(1-methyl-1H-pyrazol-4-yl)pyrazine-2-carboxamide::US20260146035, Example 71

SMILES Cn1cc(-c2cnc(N)c(C(=O)N[C@H]3COC[C@@H]3OCc3ccc(-c4ccc5c(c4)C(C)(C)CN5C4CCN(CCO)CC4)cc3)n2)cn1

InChI Key InChIKey=KNBWETGHFOIVED-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809043   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809043BDBM809043(3-amino-N-{(3S,4R)-4-[(4-{1-[1-(2-hydroxyethyl)pip...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809043BDBM809043(3-amino-N-{(3S,4R)-4-[(4-{1-[1-(2-hydroxyethyl)pip...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809043BDBM809043(3-amino-N-{(3S,4R)-4-[(4-{1-[1-(2-hydroxyethyl)pip...)
Affinity DataIC50: 550nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent