BDBM809050 6-amino-N-[(1S,2S)-2-{[4-(1-{4-[(2,2-dimethyl-1,3-dioxolan-4-yl)methyl]piperazin-1-yl}-2,3-dihydro-1H-inden-5-yl)phenyl]methoxy}cyclopentyl]-6'-fluoro[3,3'-bipyridine]-5-carboxamide::US20260146035, Example 78

SMILES CC1(C)OCC(CN2CCN(C3CCc4cc(-c5ccc(CO[C@H]6CCC[C@@H]6NC(=O)c6cc(-c7ccc(F)nc7)cnc6N)cc5)ccc43)CC2)O1

InChI Key InChIKey=NLJZJEQSYLYLOS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809050   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809050BDBM809050(6-amino-N-[(1S,2S)-2-{[4-(1-{4-[(2,2-dimethyl-1,3-...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809050BDBM809050(6-amino-N-[(1S,2S)-2-{[4-(1-{4-[(2,2-dimethyl-1,3-...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809050BDBM809050(6-amino-N-[(1S,2S)-2-{[4-(1-{4-[(2,2-dimethyl-1,3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent