BDBM809052 6-amino-N-{(1S,2S)-2-[(4-{1-[4-(2,3-dihydroxypropyl)piperazin-1-yl]-2,3-dihydro-1H-inden-5-yl}phenyl)methoxy]cyclopentyl}-6'-fluoro[3,3'-bipyridine]-5-carboxamide::US20260146035, Example 80

SMILES Nc1ncc(-c2ccc(F)nc2)cc1C(=O)N[C@H]1CCC[C@@H]1OCc1ccc(-c2ccc3c(c2)CCC3N2CCN(CC(O)CO)CC2)cc1

InChI Key InChIKey=AONFZGRKPWCQQK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809052   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809052BDBM809052(6-amino-N-{(1S,2S)-2-[(4-{1-[4-(2,3-dihydroxypropy...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809052BDBM809052(6-amino-N-{(1S,2S)-2-[(4-{1-[4-(2,3-dihydroxypropy...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809052BDBM809052(6-amino-N-{(1S,2S)-2-[(4-{1-[4-(2,3-dihydroxypropy...)
Affinity DataIC50: 550nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent