BDBM809056 6-amino-6'-fluoro-N-{(1S,2S)-2-[(4-{1-[4-(2-hydroxyethyl)piperazin-1-yl]-3,3-dimethyl-2,3-dihydro-1H-inden-5-yl}phenyl)methoxy]cyclopentyl}[3,3'-bipyridine]-5-carboxamide::US20260146035, Example 84

SMILES CC1(C)CC(N2CCN(CCO)CC2)c2ccc(-c3ccc(CO[C@H]4CCC[C@@H]4NC(=O)c4cc(-c5ccc(F)nc5)cnc4N)cc3)cc21

InChI Key InChIKey=PBFWETYQRAQFFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809056   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809056BDBM809056(6-amino-6'-fluoro-N-{(1S,2S)-2-[(4-{1-[4-(2-hydrox...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809056BDBM809056(6-amino-6'-fluoro-N-{(1S,2S)-2-[(4-{1-[4-(2-hydrox...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809056BDBM809056(6-amino-6'-fluoro-N-{(1S,2S)-2-[(4-{1-[4-(2-hydrox...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent