BDBM809063 US20260146035, Example 91::amino-2'-fluoro-N-{(1S,2S)-2-[(4-{(1S)-1-[4-(2-hydroxyethyl)piperazin-1-yl]-2,3-dihydro-1H-inden-5-yl}phenyl)methoxy]cyclopentyl}[3,3'-bipyridine]-5-carboxamide

SMILES Nc1ncc(C(=O)N[C@H]2CCC[C@@H]2OCc2ccc(-c3ccc4c(c3)CC[C@@H]4N3CCN(CCO)CC3)cc2)cc1-c1cccnc1F

InChI Key InChIKey=LKWGWQTXUMQOPA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809063   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809063BDBM809063(amino-2'-fluoro-N-{(1S,2S)-2-[(4-{(1S)-1-[4-(2-hyd...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809063BDBM809063(amino-2'-fluoro-N-{(1S,2S)-2-[(4-{(1S)-1-[4-(2-hyd...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809063BDBM809063(amino-2'-fluoro-N-{(1S,2S)-2-[(4-{(1S)-1-[4-(2-hyd...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent