BDBM809095 6-amino-5'-fluoro-N-{(1S,2S)-2-[(4-{5-[4-(2-hydroxyethyl)piperazin-1-yl]-5,6,7,8-tetrahydronaphthalen-2-yl}phenyl)methoxy]cyclopentyl}[3,3'-bipyridine]-5-carboxamide::US20260146035, Example 123

SMILES Nc1ncc(-c2cncc(F)c2)cc1C(=O)N[C@H]1CCC[C@@H]1OCc1ccc(-c2ccc3c(c2)CCCC3N2CCN(CCO)CC2)cc1

InChI Key InChIKey=VOITZQBYWPWYLP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809095   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809095BDBM809095(6-amino-5'-fluoro-N-{(1S,2S)-2-[(4-{5-[4-(2-hydrox...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809095BDBM809095(6-amino-5'-fluoro-N-{(1S,2S)-2-[(4-{5-[4-(2-hydrox...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809095BDBM809095(6-amino-5'-fluoro-N-{(1S,2S)-2-[(4-{5-[4-(2-hydrox...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent