BDBM809118 2-amino-N-[(1S,2S)-2-({4-[8,8-dimethyl-5-(piperazin-1-yl)-5,6,7,8-tetrahydronaphthalen-2-yl]phenyl}methoxy)cyclopentyl]-5-(1-methyl-1H-pyrazol-4-yl)pyridine-3-carboxamide::US20260146035, Example 146

SMILES Cn1cc(-c2cnc(N)c(C(=O)N[C@H]3CCC[C@@H]3OCc3ccc(-c4ccc5c(c4)C(C)(C)CCC5N4CCNCC4)cc3)c2)cn1

InChI Key InChIKey=ZUZQHIBQTXEQJI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809118   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809118BDBM809118(2-amino-N-[(1S,2S)-2-({4-[8,8-dimethyl-5-(piperazi...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809118BDBM809118(2-amino-N-[(1S,2S)-2-({4-[8,8-dimethyl-5-(piperazi...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809118BDBM809118(2-amino-N-[(1S,2S)-2-({4-[8,8-dimethyl-5-(piperazi...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent