BDBM809122 6-amino-N-[(1S,2S)-2-({4-[(1S)-3,3-dimethyl-1-(4-methylpiperazin-1-yl)-2,3-dihydro-1H-inden-5-yl]phenyl}methoxy)cyclopentyl]-2'-fluoro[3,3'-bipyridine]-5-carboxamide::US20260146035, Example 150

SMILES CN1CCN([C@H]2CC(C)(C)c3cc(-c4ccc(CO[C@H]5CCC[C@@H]5NC(=O)c5cc(-c6cccnc6F)cnc5N)cc4)ccc32)CC1

InChI Key InChIKey=GVSVZHFWKNDVHT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809122   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809122BDBM809122(6-amino-N-[(1S,2S)-2-({4-[(1S)-3,3-dimethyl-1-(4-m...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809122BDBM809122(6-amino-N-[(1S,2S)-2-({4-[(1S)-3,3-dimethyl-1-(4-m...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809122BDBM809122(6-amino-N-[(1S,2S)-2-({4-[(1S)-3,3-dimethyl-1-(4-m...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent