BDBM809130 2-amino-N-{(1S,2S)-2-[(4-{8-[1-(2-hydroxyethyl)piperidin-4-yl]-5,5-dimethyl-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl}phenyl)methoxy]cyclopentyl}-5-(1-methyl-1H-pyrazol-4-yl)pyridine-3-carboxamide::US20260146035, Example 158

SMILES Cn1cc(-c2cnc(N)c(C(=O)N[C@H]3CCC[C@@H]3OCc3ccc(-c4cnc5c(c4)C(C)(C)CCN5C4CCN(CCO)CC4)cc3)c2)cn1

InChI Key InChIKey=VHTHZRQHPAWBNA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809130   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809130BDBM809130(2-amino-N-{(1S,2S)-2-[(4-{8-[1-(2-hydroxyethyl)pip...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809130BDBM809130(2-amino-N-{(1S,2S)-2-[(4-{8-[1-(2-hydroxyethyl)pip...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809130BDBM809130(2-amino-N-{(1S,2S)-2-[(4-{8-[1-(2-hydroxyethyl)pip...)
Affinity DataIC50: 55nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent