BDBM809136 2-amino-N-[(1S,2S)-2-({4-[(5S)-5-(4-methylpiperazin-1-yl)-5,6,7,8-tetrahydronaphthalen-2-yl]phenyl}methoxy)cyclopentyl]-5-(1-methyl-1H-pyrazol-4-yl)pyridine-3-carboxamide::US20260146035, Example 164

SMILES CN1CCN([C@H]2CCCc3cc(-c4ccc(CO[C@H]5CCC[C@@H]5NC(=O)c5cc(-c6cnn(C)c6)cnc5N)cc4)ccc32)CC1

InChI Key InChIKey=VGODSPOQWAWFOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 809136   

TargetTyrosine-protein kinase Mer(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809136BDBM809136(2-amino-N-[(1S,2S)-2-({4-[(5S)-5-(4-methylpiperazi...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809136BDBM809136(2-amino-N-[(1S,2S)-2-({4-[(5S)-5-(4-methylpiperazi...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent

TargetTyrosinase(Human)
Dong-A St Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 809136BDBM809136(2-amino-N-[(1S,2S)-2-({4-[(5S)-5-(4-methylpiperazi...)
Affinity DataIC50: 10nMAssay Description:The reason was carried out in white low volume 384-well plate (Corning, USA) with 25 nL compounds in dimethyl sulfoxide in each well. To measure the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2026
Entry Details
US Patent